AlfaCholine Forte

AlfaCholine Forte

Fortify Your Health with Alfacholine Forte

Introducing ALFACHOLINE® Forte, our advanced patented formulation engineered to strengthen your liver, brain, and cardiovascular health while maintaining the stability and integrity of cell membrane. Utilising the natural benefits of Phosphocholine Complex to optimise your body’s essential processes, ALFACHOLINE® FORTE is the ultimate solution for elevating your overall health and well-being.


Reduction Of Visceral Fat

Optimize the elimination of triglycerides and cholesterol from the liver. Facilitating lipid breakdown and efficient transport, they act as a barrier against visceral fat accumulation in the liver.

FXR (farnesoid X receptor) Activation

FXR activation promotes the reduction of visceral fat, utilisation of lipids for energy production and promote liver homeostasis, reducing the risk for developing fatty liver.

Anti-Inflammatory Effects

Possessing both anti-inflammatory and antioxidant attributes that mitigate liver inflammation and counteract oxidative stress, ensuring the comprehensive health of the liver.

Repair and Regenerate Liver Cells

Promote the rejuvenation and revitalization of liver health by fortifying and enhancing the fluidity of the cellular membrane within the liver.

Maintains Healthy Cholesterol Levels

Reduce the LDL cholesterol uptake in gastrointestinal layer, which helps to maintains a harmonious equilibrium between HDL and LDL cholesterol, effectively reducing the risk of hypercholesterolemia.

Regulates Homocysteine Levels

Improve the choline reservoir, enabling the generation of betaine. Greater choline availability ensures ample betaine supply, supporting the reduction of homocysteine.

Improves Lipid Transport and Metabolism

Enhance lipid transport and metabolism which promote effcient clearance of cholesterol from the bloodstream, reducing the risk of plaque formation and cardiovascular disease.

Brain-boosting ingredients:

Cognitive-Enhancing Formula

Nootropic with blood-brain barrier properties, offering efficient formation of acetylcholine and uridine, a precursor for both neurotransmitter synthesis and synaptic connection, which plays a key role in memory, learning, and cognitive processes.

Preserving of Optimal Brain Integrity

Promote healthy membrane fluidity, neuroprotection, and neuroplasticity, which are essential for supporting the survival and maintenance of brain cells. This is achieved by providing structural support to cellular membranes, shielding them from oxidative stress, and maintaining their integrity. Neuroplasticity is critical for learning, memory formation, and adapting to new experiences.

THE IMPORTANCE of Phosphatidylcholine and Choline

Maintaining an optimal balance of phosphatidylcholine and choline within the body is essential for supporting organ normal functions. When these levels decline beyond the optimal level, often influenced by factors (e.g., diet, medical conditions, medication, genetics), health risks and complications may arise.

LIPOSOMAL delivery enhances efficiency

ALFACHOLINE® FORTE utilises liposomes (microscopic vesicles with cell membrane-like lipid bilayers and) to envelope and safely carry its key ingredients to the liver.

This liposomal delivery system enhances ALFACHOLINE® Forte’s bioavailability by ensuring that its constituents reach their intended target-specific organs. The liposomes reach their intended target, which is the liver. Here, they break down, releasing all the bioactive substances into the circulatory and initiating their mechanism of action.

Liver is the primary site of action for Alfacholine, their functions involve the production of VLDL and the initiation of FXR activation for lipid metabolism.Simultaneously, free Choline returns to the circulatory system, enhancing the choline pool through the hepatic vein. It then exerts its mechanism of action by reducing homocysteine and cholesterol while promoting acetylcholine production and rejuvenation of the celullar membrane.

Factors for Low Phosphatidylcholine and Choline Levels


An inadequate intake of choline-rich food (e.g., eggs, liver, meat, etc.) can result in low phosphatidylcholine and choline levels.


Existing conditions such as fatty liver disease or kidney dysfunction affects phosphatidylcholine synthesis or production of choline.


Certain medicine such as anticonvulsant drugs or cholesterol-lowering drugs may impact phosphatidylcholine and choline levels.


Genetic variations in the relevant genes (e.g., PEMT, CHDH) can influence the optimal production and utilisation of phosphatidylcholine and choline.

Frequently Asked Questions (FAQ)

Are there any risks or side effects associated with ALFACHOLINE® Forte intravenous therapy?

A: Like any medical procedure, there are potential risks and side effects associated with intravenous therapy. These may include allergic reactions, injection site reactions, or rare complications. It is important to discuss these risks with a healthcare professional.

Is ALFACHOLINE® Forte intravenous therapy safe for everyone?

A: ALFACHOLINE® Forte intravenous therapy should be performed under medical supervision. It is generally safe when administered by qualified healthcare professionals, but individual circumstances and medical history may affect its suitability. It is important to consult with a healthcare professional to determine if this therapy is appropriate for you.

Q: What is the upper tolerable dose for ALFACHOLINE® Forte?

A: When administered intravenously, the upper limit of ALFACHOLINE® Forte can vary depending on factors such as individual health conditions, tolerance, and specific treatment goals. Generally, the maximum dosage for ALFACHOLINE® Forte intravenous therapy is two vials per week with at least 1-day intervals between injections. Two ALFACHOLINE® Forte session is equivalent to 1712mg Phosphocholine Complex.

Q: Concerning diabetic patients, can normal saline be used as a replacement for Dextrose or Glucose solution to prepare ALFACHOLINE® Forte infusion?

A: No, ALFACHOLINE® Forte liposomal structure is unstable when reconstituted with normal saline; hence only use Glucose or Dextrose 5 % solution, even in diabetic patients.

Q: What is the onset of action with ALFACHOLINE® Forte intravenous therapy?

A: The onset of action with ALFACHOLINE® Forte intravenous therapy is typically rapid. Since ALFACHOLINE® Forte is directly introduced into the bloodstream, it can quickly reach its target tissues and exert its effects.

Q: What are the side effects?

A: Severely atherosclerotic patients, individuals undergoing daily treatments, or those without a gall bladder may experience temporary Diarrhea and there may be a temporary increase in LDL cholesterol and Liver enzymes at the start of treatment, which will return to normal with ongoing therapy and post maintenance therapy. Fatigue and thrombophlebitis at the infusion site are also possible side effects.

Q: How to avoid thrombophlebitis?

A. Increase the Dextrose or Glucose solution from 250ml to 500ml and the infusion time by 90 minutes – 120 minutes.

Q: What is the best storage condition?

A. ALFACHOLINE® Forte is stable under room temperature <25°C. Although ALFACHOLINE® Forte is stable at room temperature, storing the vial in a refrigerator until ready to use is advisable. All opened vials must be used immediately so as to avoid contamination. Take out the Alfacholine from the refrigerator 1 hour prior to mixing ALFACHOLINE® Forte with Dextrose or Glucose solution.

Q: Does FDA approve ALFACHOLINE® FORTE solution?

A: ALFACHOLINE® Forte is legally compounded for physician use, compliance with AMG law, Germany.

Supplement Intravenous Therapy
Administration Oral supplementation Intravenous injection
Absorption Absorbed in the gastrointestinal tract Direct into the bloodstream; the liver is the
primary site of action
Bioavailability Variable, influenced by individual factors and
digestion bioavailability 60%
Intravenous administration provides
immediate and complete absorption,
resulting in high bioavailability close to
Onset of Action Gradual Rapid
Indication of Use General supplementation for brain health,
liver support, and cognitive function.
Suitable for prevention and maintenance
Medical procedures requiring immediate
Choline and Phosphatidylcholine
administration, fatty liver and cardiovascular
conditions (homocysteine/lipid plaques).
Suitable for the corrective course.
Safety Generally safe when used as directed Requires medical supervision, potential risks
and side effects associated with intravenous
Contraindication Allergies or sensitivities to
phosphatidylcholine, choline or other
Known hypersensitivity to
phosphatidylcholine/choline, certain
medical conditions requiring caution with
intravenous administration


Infusion preparation:

Mix 10ml Alfacholine® Forte solution with 250ml of 5% Dextrose or Glucose.

Length of the infusion:

Please allow 60 – 100 minutes of infusion time.


Corrective: One-course treatment is a minimum of 10 sessions, 1 vial per session. Administration frequency is once or twice a week in a 2-to-3-month timeframe.

Maintenance: Daily oral supplementation of Alfacholine® softgel, 1 softgel per day.


4°C – 16°C, away from direct sunlight. Stable under room temperature < 25°C.

Shelf Life:

2 years


Cannot be mixed with normal saline and avoid rapid infusion.