LIPOSOMAL NMN ULTRA BOOSTER
ADVANCED CELLULAR REGENERATION FOR HEALTHY AGING
LAB RMS’s latest offering, the Liposomal NMN Ultra Booster is a world first in providing potent cellular revival properties with distinct benefits, designed to be safe and highly effective. It is uniquely formulated with FOUR therapeutic ingredients that work synergistically to enhance cellular restoration, mitigate aging-related dysfunctions, and preserves NAD-dependent mitochondrial respiration through Advanced Mitochondria-Targeted Liposomal Delivery Technology.
Liposomal NMN Ultra Booster is a non-GMO vegan product free from artificial colours, flavours, chemical preservatives, and alcohol. It consists of high-quality ingredients that are pristine, pure, and pharmaceutical-graded.
ACTIVE INGREDIENTS:
250mg NMN (β-Nicotinamide Mononucleotide)
100mg Phytowhite Tripeptide
40mg Resveratrol
10mg PQQ (Pyrroloquinoline Quinone)
CONTRAINDICATIONS:
Consult your physician before using this product, especially if you are taking any medications, are currently pregnant/nursing, or under 18 years of age. Should there be any occurrence of adverse reactions, discontinue use and consult your doctor immediately. Do not exceed the recommended dose. Keep out of reach of children.
SUGGESTED USE:
Take 30 drops (2ml) daily, mix in 100ml plain water, drink immediately. Must be consumed after meals. Dosage intake is adjustable throughout the day. You can take 10 drops after breakfast, 10 drops after lunch, and 10 drops after dinner for a total of 30 drops per day.
STORAGE:
Store at room temperature, away from light, heat, and humidity. Do not keep the product in the refrigerator.
PACKAGING:
30ml per bottle. Dropper is included.
WHY DO YOU NEED LIPOSOMAL NMN ULTRA BOOSTER?
Nicotinamide Adenine Dinucleotide (NAD+) is an important cofactor, naturally present in our cells, that declines gradually as we age. The depletion of NAD+ is highly associated with aging, and may trigger a wide range of age-related diseases including metabolic disorders, cancer, and neurodegenerative diseases. Evolving evidence indicates that by increasing these NAD+ levels, we may decelerate or even reverse the phases of aging and delay the development of age-related afflictions.
Liposomal NMN Ultra Booster’s advanced formula contains one of the best coenzymes and NAD+ precursors, paired with powerful antioxidants and polyphenol to support cellular rejuvenation via restoration of the mitochondria’s functions, optimization of life expectancy, reparation, and protection against DNA damage in the body.
Each serving contains NMN (β-Nicotinamide Mononucleotide), Phytowhite Tripeptide, Resveratrol and PQQ (Pyrroloquinoline Quinone), transported into the system through liposomes – allowing for rapid uptake and the highest bioavailability delivery at the cellular level.
BENEFITS OF TAKING LIPOSOMAL NMN ULTRA BOOSTER:
- Enhances Cellular Restoration
- Mitigates Aging-Related Dysfunctions
- Preserves NAD-dependent Mitochondrial Respiration
THE FOUR INGREDIENTS & WHAT THEY DO FOR YOU
NMN
Professionally extracted from Brassica oleracea var. italica, a biological, naturally occurring nucleotide. It’s the most established source of cellular energy, as well as the best precursor for Nicotinamide Adenine Dinucleotide (NAD+) synthesis.
Phytowhite Tripeptide
A master antioxidant that exists naturally in the body, protecting against cellular damage and sustaining xenobiotics detoxification. It aids in DNA repair, protein synthesis, amino acids transportation and enzyme activation, in addition to being key in the survival of cells, shielding them from endogenous and exogenous reactive oxygen species (ROS).
Resveratrol
Classified as one the most potent dietary antioxidants, potentially able to extend lifespan via the activation of the enzyme Sirtuin-1 (SIRT1). It has anti-inflammatory and antimicrobial effects.
PQQ
PQQ works synergistically with Phytowhite Tripeptide to induce itself to its reduced form (PQQH2) for its antioxidative power that is 7.4 times higher than that of vitamin C. It stimulates the production of new mitochondria and sustain its morphology, making it the perfect ingredient to pair with NMN.
OUR EXCLUSIVE LIPOSOME DELIVERY SYSTEM – HOW IT WORKS
Liposomal NMN Ultra Booster’s formula utilizes pristine quality phospholipids, known as phosphatidylcholine; these liposomes have a size of 1.25μm – they are micro-sized spherical vesicles with phospholipid bilayers possessing high therapeutic efficacy. The phospholipid bilayers in liposomes facilitate the modulation of bio-distribution of the active ingredients, improving its safety profile.
ADVANCED MITOCHONDRIA - TARGETED LIPOSOMAL DELIVERY TECHNOLOGY (AMTLDP)
Liposomal NMN Ultra Booster uses an exclusive Advanced Mitochondria-Targeted Liposomal Delivery Technology (AMTLDP) specifically designed to transport active ingredients directly to the mitochondria in our cells at therapeutic concentrations. These mitochondria-targeting liposomes are embedded with lipophilic cation TPP (triphenylphosphonium bromide) using phosphatidylcholine as an anchor to enable high-efficiency delivery of active ingredients. TPP is used here as it is positively-charged, which promotes endosomal escape in addition to providing improved delivery of active ingredients to the negatively-charged mitochondria.
ADVANTAGES OF ADVANCED MITOCHONDRIA-TARGETED LIPOSOMAL DELIVERY TECHNOLOGY (AMTLDT)
- Targeted mitochondria delivery system
- Liposomes shield nutrients from external degradation
- Industry-leading micro sized liposomes facilitates instant absorption
- Allow adjustable dosage
- High biocompatibility (non-toxic)
- Highly stable under room temperature and is not photosensitive, easy to store
MECHANISMS OF ACTION
1. ENHANCED CELLULAR RESTORATION
Upon the oral administration of Liposomal NMN Ultra Booster, the TPP-liposomes are directly facilitated by ENTs to enter the cytoplasm, without the need to be converted to NR. From here, the active ingredients undergo endosomal escape to target mitochondria, where they will be released. NMN will then be converted into NAD+ in the mitochondria with the help of NMNAT1-3.
In about 2 – 3 minutes, NAD+ will start to be absorbed to the blood circulatory system. Eventually, NAD+ will be entirely absorbed and stored in tissues and cells within 15 minutes, especially in body tissues such as cortex, liver, as well as skeletal muscle for energy.
2. MITIGATE AGING-RELATED DYSFUNCTIONS
Improve Metabolic Syndrome
The process of aging is affected by multiple factors, including the buildup of mitochondrial defects, DNA damage, cellular damage, and the occurrence of metabolic dysfunctions. The declined amount of NAD+ molecules further result in the aging process and lead to a shorter life’s span. Replenishing NAD+ molecules may then be a therapeutic solution via Sirtuins (SIRTs) and PARPs activation to combat these aging factors.
To understand this: one must learn the importance of NAD+. NAD+ acts as electron-shuttle to transport electrons for energy (ATP) re-formation; the maintenance of NAD+ concentration is crucial to sustain overall energy production, maximize cellular capacity and improve physical endurance. Our skeletal muscles ATP levels will then be maintained. In our cells, NAD+ molecules are constantly being consumed by Sirtuins to stimulate mitochondrial activity and delay aging.
SIRTs activation beneficial effects:
Promote Healthy Aging
Prolongs life span through activation of FOXO. which delays aging process of the body.
Improve Body Composition
Decreases formation of adipocyte (fat) tissue by repressing PARPs, and stimulates gluconeogenesis (production of glucose from the breaking down of fat or protein molecule) by PGC-1α activation.
Increase Energy Level
Induces formation of new mitochondria in the brown adipose tissue (BAT) and muscles by PGC-1α activation.
Support DNA Protection & Repair
Liposomal NMN Ultra Booster contains ingredients works synergistically to activate the enzyme PARPs. PARPs use the NAD+ in the mitochondria to detect DNA damage and initiate repair. The damage in DNA or mutation may be associated with aging.
As a sensor, PARPs detect DNA double-strand breaks (DSB). Once DSB are detected, the PARPs facilitate repair. The repair is done via communication with MRE11 (meiotic recombination 11) and ATM (ataxia telangiectasia mutated) – it is a convoluted process to avoid cell apoptosis and mutation. Therefore, PARPs maintain the stability of genes and the integrity of cells, keeping them at their best optimum health.
3. PRESERVES NAD-DEPENDENT MITOCHONDRIAL RESPIRATION
Age-related dysfunctions in the body are complications arises from cell death. The cause of cell death or rapid aging may be due to the buildup of reactive oxygen species (ROS) to damage our DNA and proteins. The therapeutic effects of Liposomal NMN Ultra Booster activates Sirtuin-1 (SIRT1) as antioxidants to keep ROS at bay. It is utilized here as natural preventive agents in preventing damage caused by oxidative stress.
In the cardiovascular system, SIRT1 activation stimulates the survival of cardiomyocytes (cells responsible for regulating the force of contraction in the heart). Subsequently, Liposomal NMN Ultra Booster may improve capillary density as well as blood flow, allowing for improved regulation of vascular homeostasis and helping with vasodilatory and regenerative functions in the endothelial cells (EC) and smooth muscle cells of the vascular wall.
SIRT1 activation helps EC to release substances to optimize vascular relaxation and contraction, together with its ability to support new blood vessels formation (sprouting). Premature senescence of EC may then be prevented. This formula also helps in protecting blood vessels from endothelial damaged caused by high glucose levels.
